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SOCKET GRAFT PUTTY™

Patented to Stimulate Osteogenesis



"...no other bone graft on the market today has been shown to stimulate osteogenesis as effectively as Socket Graft Putty™."

"Implant placement 8 weeks after extraction and grafting with Socket Graft Putty™"

 


Socket Seal with PeriAcryl




The FDA has cleared Socket Graft Putty for implant placement in 8 weeks. Most other bone grafts are not permitted to advise an implant placement in a given time frame. In addition, Socket Graft Putty™ is one of the few bone grafts on the market worldwide cleared by the FDA to claim that it stimulates osteogenesis. All this and no surgical incisions or flaps are required.


SOCKET GRAFT PUTTY™ is the only bone graft on the market that contains a drug that changes the physiology of the osteoblast to stimulate osteogenesis. SL Factor™ our patented organic compound enters through the membrane of the osteoblasts and results in the following metabolic activities.

  • SL Factor enters the through the osteoblasts’ membrane and activates over 300 genes that stimulates the process of bone formation.
  • Stimulates mesenchymal stem cells to differentiate into osteoblasts.
  • Creates a two-fold increase in BMP2 and Runx2 production and reduces osteoclast formation by inhibiting the production of RANK ligand.
  • Enhances osteocalcin accumulation in the extracellular matrix resulting in excellent mineralization.
  • Stored in the osteoblast and continues to stimulate bone growth after the synthetic matrix has been resorbed.
  • Inhibits adipogenesis, osteoclastogenesis, and ODF/RANK ligand expression in bone marrow cell cultures.
  • Reduces inflammation by inhibiting prostaglandin synthesis.

Everything in Socket Graft Putty is synthetically produced while all of the compounds exist in nature. There are no animal or human products in any of our graft materials. In addition, there is no potential for allergic or inflammatory reactions.

Affordable with ease of application and great results, Socket Graft Putty is the graft material your patients will accept when compared to other bone grafts in today’s market.



THE SCIENCE BEHIND SOCKET GRAFT™


     

Root fracture resulting in loss of mesial buccal wall of mandibular molar

Cortical Plate Used For Missing Buccal Wall

Immediate Implant Placement Without Temporary Crown
     

Root Fracture With Missing Buccal And Lingual Walls

Immediate Implant Placement With All Existing Walls

Loss Of Buccal Wall And Immediate Implant Placement In The Esthetic Zone
     

Immediate Implant Temporization In The Esthetic Zone
   
     

SOCKET GRAFT PUTTY™

Socket Graft™ is a dual phase calcium phosphate based synthetic bone graft material. Socket Graft™ is designed to quickly and economically treat the extraction socket to retain alveolar bone, stimulate bone formation and reduce post operative complications. It is designed to be quickly and completely resorbed. The insurance code for socket regeneration (preservation) is D7953. Socket Graft must be stored in a refrigerated environment between 40 and 60 degrees Fahrenheit.


DIRECTIONS FOR USE

Either syringe can be used for dispensing graft material. *White syringe has a larger bore for easy dispensing in accessible areas. *Green syringe has a tip for harder to reach areas but requires more force for dispensing. If blood is in the socket use the green syringe with the tip and fill the socket from the apex to the gingiva in order to fully displace the blood as you inject.




 
1.Hold both syringes upright and un-screw caps.
 
2.Hold the powder syringe upright & screw both syringes together. Liquid will not leak. Push liquid into powder syringe. Mix back and forth about 10 times until completely mixed.
 


 

3. After mixing, push entire graft material into the green syringe. Remove the white syringe and set aside for 3 min for graft activation to occur. During this time Socket Seal™ can be prepared according the following Socket Seal™ instructions.

4. After 3 min, place the white dispensing tip on the green syringe and Socket Graft™ is ready for use.

5. Make sure all debris is removed from the socket. Inject Socket Graft Putty™ starting at the base of the socket. If excessive bleeding is occurring it can push out the graft material. If excessive bleeding in occurring have your assistant cover Socket Graft Putty™ with a spatula while the Socket Seal™ is being prepared. Socket Graft Putty™ is not water soluble and will not wash out or mix with blood.

The graft material can be premixed 1 hour ahead of time.



 

SOCKET SEAL™

Suggested Instructions


 
Your order of Socket Graft Putty™ includes a Socket Seal™. Socket Seals™ are sterile, medical grade closed cell foam barrier membranes. Each Socket Seal™ packet is sterile and can be placed on the surgical table.
 
1. Fill the socket with Socket Graft Putty™ and smooth off any excess putty.
 
2. Cut Socket Seal™ to fit the orifice of socket. Making Socket Seal™ slightly larger than the orifice will maintain the gingival and papillary margins and provide a better seal. The Seal sits in the gingiva and above the alveolar crest
 
3. Place a suture through the buccal and lingual gingival margin. Some practitioners find it beneficial to place a suture in the seal before it is carried to the extraction site.
 
 
4. Tie the suture to stabilize Socket Seal™ and then place a few sutures through the seal when crises-crossing to prevent the seal from being displaced and close any loose papilla or lacerations in the gingiva.
 
 
5. Remove Socket Seal™ in 2 weeks. The seal is biologically active and remaining two weeks allows this activity to continue. The seal will maintain the gingival margin. After the seal is removed at post op an ovate pontic can be placed in the depression for improved esthetics.
 
 
 

SOCKET GRAFT PUTTY™

Is Easy, Quick, Non-traumatic and Affordable.

 
 

Extract, debride and graft. No incisions or flaps required.


 

Smooth off excess graft material.


 

Cut Socket Seal to size.


 

Suture according to instructions.


 

SOCKET GRAFT PUTTY™ HISTOLOGY


 

Tooth #12 was determined to be un-restorable. The socket was grafted with Socket Graft Putty™ and covered with Socket Seal™.


 

This radiograph shows the extraction site of #12 six weeks after grafting with Socket Graft Putty™.


 

Implant placement was performed at 6 weeks after extraction and grafting. At the time of implant placement a core sample was taken with the results as follows:


 

This high power photomicrograph of Socket Graft Putty™ shows osteoblasts migrating throughout Socket Graft Putty™. The vacuoles in the graft material contain SL Factor that is absorbed by the osteoblasts. The osteoblast in the upper right corner is fused with the vacuoles and is actively absorbing SL Factor. Socket Graft Putty™ is like no other bone graft material. The entire healing process is skipped and osteoblasts begin to migrate into Socket Graft Putty™ as soon as it is placed. Because Socket Graft Putty™ functions as a stimulating growth medium the graft material is populated with osteogenic cells before blood vessels arrive.


 

This low power photomicrograph is from the above socket grafted with Socket Graft Putty™ after 6 weeks. Significant bone formation has occurred and very little graft material remains.


 

This high power photomicrograph is from the previous core sample taken after 6 weeks. The mineralized bone is covered with osteoid which is lined by osteoblasts. Osteomacs are found in the canopy of cells over the osteoblasts.


 

This high power photomicrograph shows osteoblasts that have been isolated and floated over the mineralized surface. The osteoblasts are cuboidal in shape and densely packed indicating the stimulation of osteogenesis. Osteoblasts are responsible for bone formation and implant integration. The more osteoblasts present and the more stimulated the osteoblasts are directly affects your implant integration rate. Socket Graft Putty™ has the highest implant integration and long term success rates of any bone graft material. See our published research under the publications tab on our website.


 

Tooth #14 presented with caries and a buccal fistula. The gutta percha was placed in the fistula to confirm the source of the infection was the apex of the distal buccal root of #14. Significant periodontal bone loss was found mesial and distal to tooth #14. Tooth #14 was extracted and grafted with Socket Graft Putty™ and covered with Socket Seal™.


 

8 weeks after extraction and grafting with Socket Graft Putty™. Please note that Socket Graft Putty™ will regenerate bone to the alveolar crest of the extraction site. If more bone is needed ridge augmentation is indicated.


 

8 weeks after extraction and grafting a core sample was take at the time of implant placement. The sinus membrane was exposed through the implant osteotomy and raised hydraulically. The Socket was also filled with graft material and as the implant was placed the graft material raised the sinus membrane. For hydraulic lift of the sinus membrane we advise the use of Regen BioCement Flow as outlined for the Steiner Sinus Lift.


 

The core sample was evaluated with a micro CT scan to determine the morphology and physical characteristics of the bone generated 8 weeks after grafting with Socket Graft Putty™.


 

The micro CT scan reveals excellent trabecular morphology with complete resorption of the graft material at 8 weeks.


 

Horizontal radiographic cuts through the core sample shows actively growing bone nodules and excellent trabecular morphology at 8 weeks.


 

An analysis of the data derived from the micro ct scan shows an SMI of -0.02 which reflects a near ideal bone trabecular morphology. A BV/TV of 48 % indicates that 48% of the core sample was mineralized bone. This figure is higher than normal mineralized trabecular bone. TMD refers to the density of the mineralized tissue. The TMD of this sample is 809 which is well above normal trabecular bone. After 8 weeks this site grafted with Socket Graft Putty™ has produced superior bone than is found in normal trabecular bone.


 

This low power photomicrograph is from a socket after 8weeks. The top of the core sample is the original socket wall which has retained its vitality. The amount of mineralized tissue at 8 weeks has already passed the normal amount of mineralized tissue found in trabecular bone.



 

PROVEN INTEGRATION ON GRAFTED IMMEDIATE IMPLANT SURFACES WITH SOCKET GRAFT


Immediate implant placement is becoming a popular treatment option. However, no bone graft materials have been able to show that bone integration occurs in the areas of the implant that have been grafted. A failure of integration in areas not in contact with the patient's bone often leads bone defects around the coronal portion of the implant with an increase in periimplantitis. Socket Graft™ is the only implant proven to produce implant integration at the grafted site. The following case provides proof of this principal. A patient who had type 1 diabetes required good mastication to help stabilize her glucose levels. She was diagnosed with a functioning but failing lower right bridge. The patient was scheduled for removal of the bridge and placement of implants. However when she presented for surgery her lower left implant and the adjacent bicuspid had failed. The patient insisted that the left side be treated first so that she could continue to chew on her lower right bridge. The decision was made to remove the lower left implant and bicuspid and place immediate implants. Please review the following case and see how the properties of Socket Graft facilitated immediate implant placement with no bone contact.


 

Implant #19 and the bicuspid fractured and were unrestorable.



 

Upon removal of the core vent implant there was only granulation tissue present to near the mandibular nerve.



 

The socket of #19 was filled with Socket Graft and a 5.0 X 13 mm implant was floated in graft material with no bone contact.



 

The post op radiograph showed a mesial angulation of the implant #19 and a probe was used to upright the implant in the graft material. The flaps were closed with primary closure.



 

The implants were exposed and healing abutments were placed at three months. The density of bone formation appears superior in the grafted area around #19 with integration to the implant collar.



 

The restored implant establishes that areas grafted with Socket Graft produce bone integration. In this case there was no initial contact of the implant with bone. The implant has been floated in Socket Graft. The properties of Socket Graft Putty permit migration of osteoblasts as the first cells to enter into the graft material and upon reaching the implant surface integration occurs.



 

For online ordering please click on the ordering tab or call us at 866.317.1348.


STEINER LABORATORIES
590 Farrington hwy #524 Suite 132 Kapolei HI 96707
866.317.1348 www.steinerlabs.com

 
     
 
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